Allergy Treatment for Dogs and Cats

Hypo-Sensitization: The Gold Standard in Allergy Treatment

Allergen-specific immunotherapy (ASIT) is the most effective medical treatment for certain allergies. It is the only therapy that prevents allergy progression by gradually desensitizing the immune system to specific allergens.

Our customized treatment sets are tailored to each patient’s allergy profile, containing allergenic extracts designed to increase immune tolerance over time. Treatment is available in two forms:

  • Sublingual oral spray
  • Subcutaneous injections
The recommended treatment for long-term allergy relief

Allergies are lifelong conditions, requiring ongoing treatment to keep symptoms under control. While avoiding allergens is ideal, it is often impractical—especially with dust mites, grass, and tree pollen. However, certain measures can help reduce exposure.

Hypo-sensitization therapy (allergen-specific immunotherapy) is a safe and effective long-term treatment that gradually increases immune tolerance. It can be administered through:

  • Subcutaneous injections
  • Oral (sublingual) spray

Studies show that around 75% of patients respond positively, with effects typically seen after 5 months, though full benefits may take up to a year. Immunotherapy is compatible with other medications and remains the gold standard for long-term allergy management.

What to expect from Hypo-sensitization Therapy?

Every animal reacts differently to treatment, but hypo-sensitization therapy has proven to be highly effective. Studies show that around 75% of pets  experience significant improvement, often within a few months—though in some cases, results may take up to 12 months.

What If There’s No Improvement?

A small percentage of animals may show little to no response. If this occurs, it’s crucial to investigate other possible factors, such as:

  • Undiagnosed allergies (e.g., fleas, food)
  • Newly developed allergies
  • Secondary skin infections

Ongoing Monitoring & Adjustments

Regular follow-ups during the first year are essential. Treatment may require dosage adjustments or interval changes based on the patient’s response.

To ensure long-term allergy management, a comprehensive Treatment Diary is available to help track progress and optimize treatment plans. Click below to access it.

Injection Therapy for Hypo-Sensitization

Each treatment set consists of three vials with increasing potency:
🟢 Green → 🔵 Blue → 🔴 Red

  • The starting dose is 0.1 ml, gradually increasing over several months to a maximum of 1.0 ml.
  • The maintenance dose is typically reached after 13 weeks.
  • Injection intervals can be adjusted based on the patient’s response for optimal symptom control.

Treatment Schedule & Administration

  • Initial phase: Injections are administered over 9 months, with doses increasing in both volume and concentration.
  • Maintenance phase: After the first 9 months, injections continue on a monthly basis.

Customized & Cost-Effective Solutions

  • Up to 20 allergens can be included in a single treatment set for comprehensive relief.
  • Affordable pricing compared to other labs.
  • Treatment sets are prescription-based and supplied directly to the testing veterinarian by Nextmune.

A Treatment Diary is provided to help pet and horse owners track doses, monitor symptoms, and record observations for better treatment outcomes.

Sublingual Immunotherapy

Sublingual allergy drops are a great solution for pet parents or horse owners who prefer a needle-free option. If you have a patient that has an aversion to needles or has not responded well to the injections, or if the owner prefer to give daily doses, this immunotherapy can be sprayed in the animal’s mouth, in the space between the gum and cheek. This method requires daily administration and no food or drink 10 minutes before or after the drops for it to be effective! Proper and consistent administration is key.

Administering allergy drops is easy! This video shows exactly how to administer the allergy drops. Due to the addition of glycerin for stability, the treatment has a naturally sweet taste that should be enjoyable for your pet.

Short-term symptomatic medications

There are a number of short-term medications available that help to control symptoms. These symptomatic medications, such as corticosteroids, cyclosporin, oclacitinib and lokivetmab, are useful for suppressing the allergic reaction, however they do not treat the allergy itself. They can have significant disadvantages and come with side-effects, especially in the long-term.

Our recommendation is to use such products short-term and in conjunction with Hypo-sensitization Therapy, to ensure the patient is comfortable, but with a long-term goal of only administering immunotherapy for the patient’s condition.